The combined circumstantial elements and toxicological results of the case revealed the occurrence of an acute intoxication produced by U47700 Powder abuse. To the best of our knowledge, this is the first fatal intoxication case reported on the Italian territory involving the synthetic opioid U-47700.

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U-47700-d6 (Item No. 19219) is an analytical reference material intended for use as an internal standard for the quantification of U-47700 (Item Nos. 18596 | 19397) by GC- or LC-MS. U-47700 is structurally categorised  as an opioid. It is a selective µ-opioid receptor agonist (Kd = 5.3 and 910 nM for µ- and κ-opioid receptors, respectively, in guinea pig brain) that is 7.5-fold more potent than morphine (Item No. ISO60147) in animal models.1,2 U-47700-d6 is regulated as a Schedule I compound in the United States. This product is intended only for forensic and research applications. Buy u47700 with credit card, Buy U47700 powder.

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This drug is a strong μ-opioid agonist with an approximate potency 7.5 times higher than morphine. It has been available in Europe since 2014, where it is usually sold through the internet or black market as an abuse morphine like substance. In the case reported here, a Caucasian man was found dead in his apartment. Next to the body, the police seized one transparent plastic bag containing a white powder and two amber glass bottles with nasal spray containing few millilitres of a transparent liquid. During the autopsy, no evidence of natural disease or trauma was found to account for the death. Buy U47700 powder, buy u47700 with credit card

Blood, urine and pubic hair were collected and submitted for toxicological analysis. The content of the seized materials was also submitted to a general screening analysis in order to determine its composition was detected in blood, urine and hair samples using an UHPLC/MS-MS method purposely developed. The blood and urine concentrations were 380 and 10,400 ng/mL, respectively. No other drugs of abuse nor ethanol were found in blood and urine specimens. Pubic hair analysis revealed a frequent past exposure to U47700 Powder. Finally, it was identified as the main component of the powder and the liquids contained in the nasal spray bottles.



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